By: Dr. Elton Gomez, stem cell expert
A very promising therapy in several areas, since it has advantages that other treatments do not have, being loaded with growth factors derived from platelets.
Plasma Rich in Growth Factors PRGF (Plasma Rich in Growth Factors) consists of a multimolecular approach that acts simultaneously in different cell types and in different mechanisms involved in repair, such as formation of new blood vessels (angiogenesis), proliferation and cell differentiation, extracellular matrix synthesis and remodeling.
A biopharmaceutical made from the patient’s own blood, 100% compatible with patient’s tissues as an autologous derivative.
It is based on the use of platelets as a vehicle for the controlled release of different cellular signals that accelerate and optimize the repair of damaged tissues for various reasons such as surgical treatment, trauma or disease. Platelets contain many substances but in very small concentrations that have nothing to do with pharmacological doses to which we are most accustomed. Growth factors are proteins with an essential role in the tissue regeneration process.
These proteins intervene in cellular communication as they transmit their information by interacting with receptors located on the cell membrane. They also act simultaneously in different cell types and trigger biological effects such as directed cell migration (displacement called chemotaxis), cell proliferation and differentiation, formation of new blood vessels (angiogenesis), etc. All of these are fundamental events in tissue repair and regeneration. The aim of the use of PRGF is to imitate and optimize along with it the physiological mechanisms of repair that are spontaneously set in motion in all tissues after injury, whether caused by trauma, surgical treatment or disease.
MAIN MEDICAL AREAS OF APPLICATION OF PLASMA RICH IN PLATELETS AND THEIR INDICATIONS:
- Osteomuscular: Tendinopathies, meniscopathies, ligamentous lesions, fractures oseas, fascitis, muscular tears, and osteoarthritis.
- Surgical wounds: Abdominal surgery, cardiovascular, plastic cutaneous and corneal, diabetic, vascular, by pressure.
- Burns: Cutaneous and corneal.
- Chronic ulcers: Diabetic, by pressure.
- Ophthalmology: Corneal ulcers, dry eye.
- Otorhinolaryngology: Tympanoplasty.
- Cosmetics: Facial expression lines, hair implants.
- Nerves: Suture of peripheral nerves.